The world’s only interactive tool for functional and taxonomic whole genome shotgun metagenomics analysis and visualization. Developed by our co-founder Professor Daniel Huson.
Includes an up to date version of KEGG, the most comprehensive biochemical pathway database. Harness the power of this database without having to perform additional analysis steps, right after importing your alignments.
Our award-winning weighted Lowest Common Ancestor (LCA) algorithm makes taxonomic classification more precise than any alternative approach.
Intuitively develop scripts of your analysis workflows based on the commands displayed in the message window while performing your interactive analysis.
MEGAN6 offers new visualization techniques to facilitate interpretation and data-driven decisions.
To make your visualizations stand out, MEGAN6 provides user friendly color presets for every visualization in the program.
The new samples viewer makes it easy to manage your samples. Add study metadata, subset your data or remove samples with ease.
The included DAA-meganzier allows for direct import and ‚MEGANization‘ of a DIAMOND Alignment Archive (DAA), saving time and effort. DAA is now readable by MEGAN in only a fraction of the time.
The Ultimate Edition comes with a KEGG license to use the KEGG Pathways and visualizations from within MEGAN. In addition to the Taxonomy, InterPro2GO, eggNOG, and SEED database mappings, the Ultimate Edition gives you access to additional databases such as KEGG, PFAM and RDP.
Besides the new InterPro2GO mapping, the Ultimate Edition supports the usage of the latest KEGG classifications and metabolic pathways (inclouded with a MEGAN Ultimate License).
With MEGAN’s commandline tools such as Blast2RMA or the meganizer, you are able to quickly convert alignment files produced by BLAST or the fast aligner DIAMOND to a RMA or MEGAN readable DAA file. This saves you a lot of computation time. Ultimate Edition comes with a commandline mode for MEGAN preparing for using MEGAN in automated pipelines. Additionally, the Ultimate Edition provides you with NCBI taxonomy, InterPro2GO, eggNOG, DIAMOND, KEGG, SEED and Silva tailored commandline tools.
Visualizations are key in understanding your dataset. MEGAN allows you to visualize your data the best way possible, therefore you are given visualization tools to create stunning figures and charts. This includes stacked bar and stacked line charts, radial space filling trees, and word clouds. Additionally, you can create attribute correlation plots, co-occurrence plots, and heatmaps.
|Download Links||Community GitHub page||Ultimate Edition Latest Version|
|Databases, Ontologies, Resources||Taxonomy (NCBI, GTDB)
|Taxonomy (NCBI, GTDB)
|Plots: a few examples||Bar
Radial space filling trees
Attribute correlation plot
… Constantly adding new ones, submit your request
|Command-Line Tools||Blast2RMA Meganize||Blast2RMA Meganize
NCBI taxonomy tools
|Extensions||Community-generated||Latest KEGG classification and pathways (KEGG License included)
|Updates||Occasional bug fixes No new features||Regular bug fixes All new features as they are added|
|Support||MEGAN Community page||MEGAN Community page email support
Questions answered by developers
|Licensing||GPL 3||Licensed by Computomics|